Abstract: The Three Gorges Reservoir area is the special geographical unit of the Yangtze River economic belt. The mismatching of its social infrastructure construction and urbanization development will have negative impact on the long-term sustainability inthis area. Based on the panel data of Three Gorges Reservoir Area in 2000-2014, this research built up the framwwork of measure system of Social Infrastructure and New Urbanization. The correlation model was used for detection, and the quantitative analysis of the Coordination Degree in 15 years was done through the Static Coordination Degree model to test. The results show that: (1) the Social Infrastructure construction is closely related to the Urbanization process; (2) in time, the Coordination Degree of the Social infrastructure and New Urbanization by the measurement system in the reservoir area shows a development trend from coordination to imbalance; (3) in space, the difference is obvious for the different counties and districts in the reservoir area, and it is necessary to promote the coordinating development of Social Infrastructure and New Urbanization by consideration of the specific situation of the social and economic development in different areas.