Abstract: Based on the data of the minimum travel time between every two provincial cities and the comprehensive index of socioal economy, we used weighted average travel time indicators, modified gravitational model, geostatistical analysis, spatial exploratory analysis and spatial econometric model to explore the urban accessibility and spatial connections of Central Plains city group. Results are shown as follows: First, the spatial pattern of the regional accessibility forms a cross axis shape like ‘十’, the accessibility of cities along the north-south direction is superior to that of east-west cities. Locally, The statistical of Moran’s I shows the characteristic of spatial clustering, and the significant spatial association types are dominated by significant HH and significant LL. Secondly, economic linkages present a three-dimensional network shape like a diamond, which structure not only has an obvious hierarchy feature, but also be characterized by gathering small groups, close ties within the group, as a whole is relatively loose links. The local space pattern highlights the radiated characteristics of central cities such as Zhengzhou, Shangqiu and Luoyang. Thirdly, the urban size, urbanization level, transportation condition, urban location and resource circulation capacity would account for the intensity of economic connections and spatial relationship in Central Plains city group.