Abstract: Abstract：This article aims to reveal the coupling coordination degree among economic development, spatial development and environmental evolution, and the coupling coordination degree between any two systems in the Pan-Yangtze River Delta region in 2005, 2010 and 2016. In this paper, the index system have been built embodying these three aspects, based on the coupling coordination model, the spatial-temporal pattern and the rule of coupling co-evolution of coordination degree of economic development, spatial development and environmental evolution, and the coupling coordination degree between any two systems were examined comprehensively. Main results for this study are as follows: 1) The coupling degree of economy development, space exploitation and environment evolution exhibited significant difference spatially and temporally; to be specific, it presented a spatial pattern of “high in the northeast and low in the southwest”. In the time dimension, it is in an evolutionary trend close to the “S” type. 2) The coupling coordinating degree of economy development, space exploitation and environment evolution has a certain correlation with the spatial distribution of its coupling degree, it presented a spatial pattern of “high in the middle and east, and low in the south and north”. In the time dimension, it is in an evolutionary trend close to the growth curve of the inverted “U” type. 3) There were obvious differences of coupling coordination status between any two systems, the coupling coordination of economy development and space exploitation had the poorest condition. Thus, it is the key direction to be strengthened and optimized in the future; whilst the coupling coordination between economy development and environment evolution had high coupling coordination condition; and the coupling coordination of space exploitation and environment evolution had increased faster.