Abstract: The industrial ecology is an important way and inevitable choice to realize a sustainable development of China’s economy and society. When taking a look at the concept of modern industrial ecology, we must closely follow the nature of industrial development to build an index system. It is able to scientifically measure the level of industrial ecologization with the method of factor analysis which deeply analyzes the spatial differentiation characteristics and spatial correlation of the industrial ecology with the ESDA method. Then mining the key influencing factors of industrial ecologization using geographic detector model. The results show that: (1) The industrial ecology of the Chongqing Metropolitan Area has significant advantages, the development power of Chongqing northeast urban agglomeration is insufficient, and  there is a short board effect in the industrial ecology of the “two clusters region”. (2) The city’s industrial ecological level presents a significant “core-edge” distribution characteristic, and the links of industrial energy conservation and reduction in emissions in the counties around the main urban area are relatively weak. (3) The city’s scale power and the spatial pattern of energy conservation and reduction in emissions are relatively stable. The radiation effect of the industrial ecology in the main urban area was found to be significant, and the gap of the industrial output efficiency has been gradually shortened. (4) There is a significant spatial correlation in the industrial ecology, and the spatial agglomeration effect has been increasing gradually. (5) The main influencing factors are the following. Industrial waste gas emissions per unit of the GDP, GDP per capita, total increase in secondary and tertiary industries, and the number of R&D personnel per one million people.