Abstract: The simulation of carbon emissions and carbon sequestration under different scenarios and the prediction of carbon peaking and carbon neutrality are the keys to developing the path of "Double Carbon" goals. In this paper, the improved IPAT model and InVEST model were used to estimate and predict the carbon emissions and carbon sequestration in the Yangtze River Delta during 2010—2060. The spatio-temporal variation characteristics as well as the time of carbon peaking and carbon neutrality were analyzed. It was found that: (1) During the study period, the spatial variations of carbon emissions in the Yangtze River Delta showed a positive growth trend, with the mean annual carbon emissions of 6 317.30 t·km-2. The growth rate of carbon emissions gradually decreased outward from the core area of the Shanghai Sea. The carbon sequestration showed a spatial pattern of high in the south and low in the north, with the mean annual carbon sequestration of 607.23 t·km-2. (2) In the baseline scenario, Shanghai, Jiangsu and Anhui provinces would reach their carbon peaks in 2030, while Zhejiang Province might reach its carbon peak in 2040. In the sustainable development scenarios, all provinces might reach carbon peaks in 2030. Under the scenario of rapid economic development, all provinces would reach their carbon peaks in 2040. (3) By 2060, the three provinces and one city in the Yangtze River Delta would not be able to achieve carbon neutrality as a whole under the three scenarios. However, at the prefecture-level city level, 10 cities could achieve carbon neutrality by 2060, in the base scenario; Under the sustainable development scenario, 21 cities could achieve carbon neutrality; Under the scenario of rapid economic development, two cities could achieve carbon neutrality. Therefore, it is necessary to optimize and upgrade the energy structure, guide the rational layout of low-carbon industries, optimize the land use structure, pay attention to ecological environmental protection, in an attempt to achieve the "Double Carbon" goals.