Abstract: With a deep fusion between the two fields of biotechnology and pharmaceutical technology, enterprises in the biopharmaceutical industry are often difficult to independently complete the entire process from products' R&D to their marketing. Therefore, networking based on various kinds of links, such as knowledge transfer and co-operation, is of great significance for the development of the biopharmaceutical industry. This study constructed a relational network for the biomedical industry in three dimensions: capital, technology and connections. The relational spatial evolution characteristics of the three-dimensional network were analyzed and the spatiotemporal pattern of the power system on the national scale was explored. The dominance effect of the network power of the cities inside and outside the Yangtze River Delta region was studied. The spatial organizational pattern of the biomedical industry in the Yangtze River Delta was generalized.It is found that: (1) In terms of community evolution, the biomedical industry's funding network was centered on Shanghai, with increasingly close communications and interactions. The technology network was gradually forming large communities centered on Beijing and Shanghai. In particular, the Shanghai community attracted a large number of cities within the Yangtze River Delta. In this region, the network of individuals had progressively coalesced to formulate a significant community, with Shanghai as its hub. Nanjing and other cities had undergone a transformation of shifting from a state of detachment to a pattern of reconnection. (2) In terms of the power system, the network of relationships of this region had evolved from an extended structure to a diffuse structure, and the concentration of power of the head cities in the network went hand in hand with a tendency of moving towards the discrete distribution of resources. (3) In terms of spatial organization patterns, the Yangtze River Delta had been transformed from "centripetal" to "centrifugal" and then to "nested chain", with the internal structure of an optimized integration and an enhanced external radiation. (4) Follow-up research directions were also proposed in three areas, including the formulation of regional innovation policies, the impact of scale restructuring on regional policy boundaries, and the role of pioneer in the demonstration of regional integration for the Yangtze River Delta.