Abstract: Affected by climate, topography and other factors, meteorological drought index has different performance in different areas. Sichuan Province, located in the upper reaches of the Yangtze River, has complex geomorphic conditions and diverse climate types. Its applicability needs to be evaluated before using the meteorological drought index for drought monitoring. In this paper, we used the daily precipitation and daily mean temperature data of 34 meteorological stations in Sichuan Province from 1987 to 2016. Based on SPI index, SPEI index and MCI index (added in the new national standard document of 2017), by using some methods of time series analysis and spatial interpolation, the drought processes and drought years from 1987 to 2010 were analyzed. By means of the established RMSE (Root Mean Square Error) index and scoring method, the consistency of drought intensity and drought range reflected by multi-time scale indices was mainly studied. The results show that: (1) In general, applicability of MCI index is the best and SPI index is close to the SPEI index; On a specific monthly scale, MCI, SPI 3 (3 months), SPEI 3 (3 months), are the top three in the applicable ranking. (2) From the perspective of geographical division, the eastern Sichuan Basin is suitable for MCI index, the southwest mountainous area of Sichuan is suitable for SPI 3 index and the northwest Sichuan Plateau is suitable for two indices of SPI 6 (6 months) and SPI 1 (1 month). (3) The monitoring error of SPI, SPEI and MCI index in eastern Sichuan Basin is the smallest, followed by that in the southwest mountainous area of Sichuan, and the largest in the northwest Sichuan Plateau.