Abstract: Clarifying the relationship between urban renewal and ecological resilience is a necessary condition for promoting the construction of ecological civilization and realizing green development. By constructing an index system of urban renewal and ecological resilience，and using models such as entropy weight method and responsiveness，this paper studied the spatio-temporal evolution characteristics of urban renewal and ecological resilience in the Chang-Zhu-Tan urban agglomeration from 2010 to 2021. The response relationship between ecological resilience and urban renewal was further analyzed. The results showed that: (1) The comprehensive index of urban renewal and ecological resilience of the surrounding Chang-Zhu-Tan urban agglomeration showed an upward trend. (2) During the expansion of the high-index area of urban renewal and ecological resilience from Changsha to the surrounding cities，the low-index area continued to shrink and gradually evolved into a high-value area. (3) The response index of ecological resilience to urban renewal in the Chang-Zhu-Tan urban agglomeration generally showed a gradually decreasing trend.