Abstract: In order to realizing regional collaboration of spatial governance, it is important to explore the spatial network characteristics of urban construction land use efficiency and to develop cross-regional collaborative governance paths based on them. Therefore, this paper explored the theory of the spatial networks about urban construction land use efficiency; took 110 prefecture-level cities in the Yangtze River Economic Belt as the research units and measured urban construction land use efficiency from 2008 to 2019 using stochastic frontier analysis (SFA); select improved gravity model and social network analysis (SNA) to mine the spatial network characteristics of urban construction land use efficiency; and finally based on the theoretical path of collaborative governance of urban construction land use efficiency by block model analysis, differentiated collaborative governance paths of urban construction land use efficiency in the Yangtze River Economic Belt was constructed. The results showed that: (1) urban construction land use efficiency in the Yangtze River Economic Belt has been increasing year by year, but the uneven characteristics of different units have been existing; (2) urban construction land use efficiency in the Yangtze River Economic Belt has significant characteristics of spatial network and well-connected network structure, but the strength of the networks tend to decrease over time; (3) the core-edge structure of the spatial networks are clear, and the role and influence of each node city in the spatial networks of urban construction land use efficiency is complex and diverse; (4) spatial networks in urban construction land use efficiency show clear spatial clustering patterns, and are divided into "Net spillover plate", "Main beneficiary plate" and "Broker plate", collaborative governance of urban construction land use efficiency in the Yangtze River Economic Belt needs to be carried out according to the connotations of different plates. The study can provide reference for the formulation of collaborative governance paths to improve urban construction land use efficiency in the Yangtze River Economic Belt or other regions.