Abstract: The adaptation of environmental regulations to the green transformation of the tourism industry is a key link in achieving high-quality development of the tourism industry. It is also an inherent requirement for building a modern harmonious coexistence between humans and nature. This article evaluated the adaptability of environmental regulation and green transformation of the tourism industry in the Yangtze River Economic Belt from 2010 to 2022. The methods of kernel density estimation and GTWR model were used to reveal the spatiotemporal dynamic characteristics and the associated influencing factors. The results indicated that: From 2010 to 2022, the formal environmental regulations and green transformation of the tourism industry had undergone an evolution process of "unsuitability relatively adaptation unsuitability", with a degree of dispersion changing from "decrease increase decrease"; From 2010 to 2022, informal environmental regulations and the green transformation of the tourism industry transitioned from being fairly adapted to being relatively adapted, and the differences within the study area were gradually narrowed. In 2010, the formal environmental regulations and green transformation of the tourism industry were mainly incompatible, while in 2016, they were mainly in a better compatible. In 2022, Anhui and Sichuan showed significant "leading" characteristics in relative compatibility; In 2010, there was a significant imbalance in the adaptation of informal environmental regulations to the green transformation of the tourism industry. In 2016, a spatial pattern of "high in the north and low in the south" was roughly formed. In 2022, only Zhejiang and Yunnan were in the stage of adaptation. In the formal environmental regulation and green transformation adaptation system of the tourism industry, the negative impact of urbanization and government regulation increased from upstream to downstream, while economic development and technological innovation mostly had a positive impact on the entire basin; In the adaptation system of informal environmental regulation and green transformation of the tourism industry, urbanization and government regulation had a positive impact on most of the provinces, while technological innovation had an overall negative impact on the adaptability of the entire basin. Financial support had a positive impact only on upstream areas.