Abstract: As science and technology innovation resources gradually shift from a technology-driven and demand-driven linear model to a cooperative spatial network model,it is of great significance for regional science and technology innovation to explore the characteristics of its spatial pattern and network structure,and analyze the reasons for its formation.This paper uses the Arcgis visualization and social network analysis method to analyze the spatial pattern and network structure character of science and technology innovation resources in the Yangtze River economic belt from 2004 to 2017.The results show that: (1)the sci-tech innovation resources aggregation ability of the Yangtze River Economic Belt is gradually increasing, the polarization is serious, the gradient from east to west becomes weaker,and it have the characteristic of “leading-pursuing-following type” obviously;(2) the spatial network of Science and Technology Innovation Resources gathering ability is becoming more and more intensive,the network density presents the downward trend,the network grade,and the network efficiency present the upward trend;(3) the ability of sci-tech innovation resource aggregation of the top ten cities is more connected with other urban spatial networks, and plays a central and dominant role in the networks;(4)plate 1(33 cities including Shanghai and Nanjing) belongs to the “net spillover” plate,plate 2(26 cities including Chongqing and Chengdu) belongs to the “broker” plate,and plate 3(41 cities including Wuhan and Changsha) belongs to the “bidirectional spillover” plate Plate 4(Guiyang, Kunming and 29 other cities) is a “net beneficial” plate.According to the above conclusions,this paper puts forward some policy suggestions from the following aspects:vigorously develop new types of infrastructure,promoting scientific and technological innovation in core cities and promoting the construction of sci-tech innovation resources cooperation platform.