Abstract: As a supplement to physical space, the study of cyberspace provides a new interpretation and consideration for spatial pattern and organizational structure of a city region. Based on the information flow data of Baidu Index, this paper explored the directional and hierarchical characteristics of intercity information flows in the cyberspace of the Yangtze River Delta（YRD) region in 2018 through city’s indegree and outdegree, intercity inflows and outflows, and nodal region analysis. The results are as follows:（1) In terms of city’s indegree and outdegree, Shanghai, Hangzhou, Suzhou and Nanjing are of high influence and attraction. Hefei has strong influence in but weak attraction to other cities. Cities with both low indegree and outdegree are mainly located in Anhui province.（2) In terms of intercity inflows and outflows, Hangzhou’s strong influence is mainly in the cities of the same province, and Nanjing’s is in cities along Shanghai-Nanjing-Hangzhou corridor while Suzhou‘s is mainly in coastal cities. Shanghai has strong outflows to cities in Jiangsu and Zhejiang provinces whereas cities in Anhui province integrate into the YRD information network through the hub of Nanjing, thus presenting an overall low participation.（3) In terms of nodal region analysis, the cyberspace of YRD forms a cross-regional hierarchical nodal region with Shanghai as the dominant center, Nanjing as the secondary center and Hefei as the tertiary center, and a local nodal region of Zhejiang province with Hangzhou as the center and Ningbo as the secondary center. On this basis, this paper also made a preliminary analysis of the driving factors and puts forward some policy suggestions.