Abstract: Space of flow can be used to effectively depict the remote investment network of enterprises in special regional urban agglomeration. Based on the registration data of industrial and commercial enterprises and land use data, this paper adopts the equity penetration method to obtain the remote investment data of industrial and commercial enterprises in 42 counties and districts from 1950 to 2020 and reveals the structure and evolution characteristics of the remote investment network of enterprises around Poyang Lake urban agglomeration from the level of “main node-backbone path-spatial pattern” respectively. The research results show that: (1）The weighted in-degree of nodes gradually increases, the radiation driving effect of Nanchang is significant, the problem of unbalanced net flow spatial distribution is prominent, and the characteristics of location tendency are obvious. (2）The backbone path mainly occurs in Nanchang, Jiujiang, Yingtan, Fuzhou, Jingdezhen, and other municipal districts with good economic development, which crosses the obstacles of geographical elements. (3） The industry as a whole is developing towards a multi-center structure, and the remote investment network structure of wholesale and retail enterprises has evolved from a single center to a multi-center, the trend of the financial industry is to evolve to multiple places, flat level, and the interworking pattern, the leasing and business service industries have evolved into triple centers, and the manufacturing industry shows a trend of moving south and east.