Abstract: It plays a practical and guiding role in promoting the green and coordinated development of Yangtze River Economic Belt by measuring industrial green transformation efficiency, ecological civilization construction quality, and the synergistic effect. The research of this paper is based on provincial data during 2011 to 2017 in a national perspective. Measure industrial green transformation efficiency in Yangtze River Economic Belt by Super-SBM model. Measure ecological civilization construction quality in Yangtze River Economic Belt by entropy weight method-topsis evaluation model. Research synergetic effect between industrial green transformation and ecological civilization construction in Yangtze River Economic Belt by builting coupling coordination degree model. The results show that industrial green transformation efficiency in Yangtze economic belt is lower than the national average, and the spatial pattern of the upper, middle and lower reaches in Yangtze economic belt is progressively increase. The industrial green transformation efficiency between provinces are significant differences. The ecological civilization construction quality in Yangtze River Economic Belt is basically the same as the national average, and the spatial pattern of upper, middle and lower reaches in Yangtze River Economic Belt show a “V”, but the inter-provincial difference is small. The synergy coefficient between industrial green transformation efficiency and ecological civilization construction quality in the provinces of Yangtze River Economic Belt are generally low, and this situation is becoming more and more significant. The main reason is that ecological civilization construction lags behind industrial green transformation. We suggest that local governments should pay more attention to the coordinated development between industrial green transformation and ecological civilization construction, as well striving to reverse the situation that ecological civilization construction lagging behind industrial green transformation. In particular, they must strengthen the protection of landspace and the ecological environment, and promoting agriculture and industry of upper and middle reaches in Yangtze economic belt develop towards a ecological way. Simultaneously, it is very important to popularize ecological culture among citizens, and improve the governance system of ecological security.