Abstract: The study of tourism spatial structure helps sort out the development pattern of a tourist destination, exploring the innate laws of development, and problems to guide the sustainable development of the tourist destination. Targeting 13 prefecturelevel cities in Jiangsu Province, this thesis adopts transportation accessibility research and revisited field strength model on the basis of constructing comprehensive tourism index system to measure the comprehensive tourism strength and tourism field strength of each prefecturelevel city in four different research time spans, which are the years of 1996, 2002, 2010 and 2016. The results are capable of reflecting regional difference of comprehensive tourism strength in Jiangsu Province, and tourism field strength spatial structure features as well as their dynamic evolution process, which can lead to the evolution stage of tourism spatial structure in Jiangsu Province. Finally, its influencing mechanism can be explored based on geographic detector model. During the process, the revisited field strength model and the geographic detector model can provide a new insight and approach to the study of regional tourism spatial structure. The study of evolution stage of tourism spatial structure of Jiangsu Province and influencing mechanism can further promote regional tourism cooperation in Jiangsu Province, providing reference for sustainable development of regional tourism.