Abstract: As one of the top greenhouse gas emitters, Jiangsu province is also severely affected by climate change. Hence, Jiangsu province should take the responsibility and obligation to achieve carbon peak ahead of the national plan. Based on the LEAP and WEAP models, this paper constructs a bottom-up model for energy and water resources synergistic management, which is used to explore the potential carbon peaking paths in Jiangsu Province and its impacts on energy and water resources. The results show that: (1) Under the comprehensive policy scenario of industrial structure adjustment, energy intensity reduction, promotion of clean energy use, and power structure optimization, Jiangsu province can achieve a rapid carbon emission peak in 2028, and the main contribution to emission reduction comes from industrial and transportation sectors. (2) The adjustment of industrial structure and the reduction of energy intensity can bring about 43.8 million tons of standard coal of energy-saving effect. (3) Climate change will intensify the competitive use of water resources in different sectors, while industrial restructuring, energy intensity reduction, promotion of clean energy use and power structure optimization, and other measures can alleviate the pressure on water resources in different sectors. The fast peak-reaching scenario can bring some 11.8% of water-saving effect.