According to the newly revised “Law of the People’s Republic of China on Soil and Water Conservation”, the delimitation of Soil and Water Lossprone Areas is significant and the new Soil and Water Conservation Program is quite necessary. It’s different between assessment on “Sensitivity to Soil and Water Loss” and “Soil and Water Lossprone Areas”. In rapid urbanization areas, the artificially pressure should be emphasized in the research of Soil and Water Lossprone Areas. The plain area of Jiangsu Province is determined to be the studied area which is around 8.21 km2. Based on the “PressureStateResponse” conceptual model, an index system of twelve indices is established to delimiting Soil and Water Lossprone Areas. The pressure index, which describes the pressure that human activities or nature factors exerting on the soil and water environment, consists of landuse intensity of human disturbance, population density, fixedasset investment, distance to the city, distance to major transportation routes, average annual precipitation, relief of topography, soil erodibility Kfactor, vegetation coverage, and river density. The state index, which relates to the situation of the soil and water loss, is composed of the ratio of soil and water loss areas. The response index, which reflects the reaction of human beings to protecting environment, is defined as the areas protected by the Ecological Red Line. The indices weight is obtained with the improved classical analytical hierarchy processes. Through digitizing, the spatial database including the indices’ maps and their attributes data is built in ArcGIS software. Each index map is converted into grid format with size 250 m×250 m. Then each index is classified into several classes with regard to their changing in Jiangsu, and each class is valued with 1/3/5/7/9 according to their impacting degree on soil and water loss. Subsequently, the values of the indices classes are multiplied by derived weights for each index and then are summed together. Furthermore, the evaluation and analysis is made separately from the three sublevel indices of pressure, state, response and the general index. The results showed that the distribution of the pressure which would cause soil and water loss is common in the plain area of Jiangsu Province. The area of Ⅲ degree and above pressure accounts for 40.75%, and artificially pressure is greater than the natural pressure both in grade and area. The areas ofⅠ to IV degree Soil and Water Lossprone Areas accounts for 10.12%, 42.90%, 25.73% and 1.24%, respectively. There is no V degree Soil and Water Lossprone Areas. Finally, the regions confirmed as the Soil and Water Lossprone Areas of Jiangsu Province accounts for 26.97% of the total area, mainly distributed in the regions such as the urban district and suburb of the city and the county, urban area of the town, and development zones, as well as the Coastal Plain Sandy Area, the Highcontent Sands in Tongnan Area, and the Disused Sandy Districts of the Yellow River. The evaluation results of the units which have soil and water loss data are consistent with the actual situation, indicating that the results can basically reflect the characteristics and statue of soil and water loss in Jiangsu Province. The result can be used as an important basis for Soil and Water Conservation Planning in Jiangsu Province.