Abstract: The realization of national park management goals depends on the support of a large amount of monitoring data and information. However, different management districts of national parks often have different management goals, therefore having different needs for monitoring data and information. In order to meet the different needs of the management in different management districts of national parks and improve the monitoring pertinence and efficiency of the ecological monitoring indicator system, this research discussed the feasibility of building an ecological monitoring indicator system for the national park based on different management districts, and constructed the ecological monitoring indicator system of two management districts in the Shennongjia National Park with the method of establishing an ecological monitoring indicator system of national parks oriented to management objectives. The results showed that there were differences in the monitoring content and monitoring indicators between the two management districts, reflecting the differences in management objects of the two districts. To a certain extent, it demonstrates that the ecological monitoring indicator system based on the management zoning is more targeted. It can not only meet the monitoring needs of different management districts, but also provide a reference for the construction of the ecological monitoring indicator system of different management districts of national parks in China.