Abstract: The balance of supplies and demands of ecosystem services (ESs) is of great significance to regional sustainable development. At present, the analysis of the driving forces of supplies and demands for ESs in regions with high spatial heterogeneity needs to be further deepened. In this study, 6 ESs including water yield, grain yield, carbon sequestration, water retention, soil conservation and recreation services in Sichuan Province were calculated. Meanwhile, the surplus, deficiency and their spatial aggregation patterns of the 6 ESs were also analyzed. Finally, in order to provide the evidences for partitioning management in Sichuan Province, the key driving forces of supplies and demands of ESs at provincial and ecoregional scales were carried respectively by using RDA. The results showed that: （1) All the 6 ESs were in surplus generally; （2) The distributions of supplies and demands of 6 ESs, the state of surplus and deficits as well as the spatial aggregation pattern revealed obvious spatial heterogeneity, which were highly correlated with ecoregions; （3) Precipitation, cultivated land, slope and gross domestic product were important driving forces leading to the highly spatial heterogeneity of supplies and demands of ESs in Sichuan Province. However, scale effects of the impacts of different driving forces on ESs were observed between provincial and ecoregional scales. Besides, obvious differences in the types, orders and directions of the main driving forces of ESs can be observed at different ecoregions, which indicated that it is necessary to explore the driving forces of supplies and demands of ESs at the different regions in Sichuan Province or other areas with high spatial heterogeneity.