Abstract: Landscape ecological pattern is the foundation of regional ecological security and sustainable development. The article takes the shale gas development zone along Wujiang River as an example. Based on data of remote sensing images and shale gas development scale in 2010 and 2020, the mobile window is used to obtain the landscape pattern index, calculate the landscape ecological risk index, and build an ecological network. Explore the direct impact of shale gas development on the regional landscape pattern and the indirect impact of the ecological pattern. The results show that: (1) The forest, cultivated land in the shale gas development zone along Wujiang River have decreased by 52.78 km², 43.78 km² respectively, the construction land grew by 92.04 km². and the grassland and water land remained unchanged. The landscape aggregation index and the largest patch index in the shale gas mining area fell by 9.36%-30.61% and 14.36%-57.69% respectively. The patch density and separation index rise by 25.29%-55.39% and 2.57%-5.11% respectively. The landscape ecological risk index went up by 0.2%-0.52%, from 2010 to 2020. (2) The land damage caused by infrastructure construction such as well sites, pipelines and roads affect the surrounding landscape ecology. Among them, the patch density index and landscape ecological risk index along the road have the largest increase of 50.95%-54.28%, 0.59%-0.62%, the impact on the ecological environment is obvious. (3) In the past decade, the area of ecological sources along Wujiang River has reduced by 250 km², the number of ecological nodes has risen by 10, the length of corridors has increased by 55 km. The obstacles of biological flows, and the instability factors have increased. Shale gas development has enhanced the surface disturbance along Wujiang River with a cumulative effect. As the scale of the well site expands, the landscape and ecological pattern respond significantly. The research provides a new perspective for in-depth understanding of the impact of regional shale gas development on the landscape and ecological pattern, and the development of targeted ecological protection and restoration.