Abstract: Abstract：It is of great significance to explore the spatial distribution of land use on different terrain gradients in peak-cluster depression area,which can help regional the land management and ecological restoration.Based on the 2018 Google Earth high-resolution image(0.5 m resolution) and 30 × 30 m DEM data, we calculated the topographic  index, topographic distribution index, diversity index, and land utilization comprehensive index to analyze spatial distribution pattern of regional land use on terrain gradient of the typical peak-cluster depression in Guizhou.The conclusion shows that:(1) The four typical land use types in peak-cluster depression area are mainly dry land, woodland and shrubland; land use types have significant hierarchical characteristics on terrain gradients: residential areas, paddy fields, irrigated land, dry land, and industrial and mining landhave distribution advantages in low terrain gradient areas, and woodland and shrubland have advantages in medium and high terrain gradients.(2) With the increase of terrain gradient, the diversity index and land utilization comprehensive index of land use degree of the four study areas all showed a decreasing trend, and in the low terrain position, Wangjiazhai> Houzhaihe> Huajiang> Maolan, on the mid-high terrain, Wangjiazhai> Huajiang> Houzhaihe> Maolan.Due to the different natural environment of peak-cluster depression and the influence of socio-economic development and policies, the differences in the spatial distribution patterns of land use types in the four study areas.The research results can provide reference for land use planning and land resource allocation in typical peak-cluster depression area.