Abstract: Multifunctionality of land use is not only an important means to alleviate the conflict between human activities and land, but also a crucial factor in achieving sustainable development. This study focused on the Han River Basin as the research area and aimed to define the interaction mechanism between land use functional networks and urban-rural integration. By employing comprehensive methods such as land use multifunctional evaluation, social network analysis, and spatial metrology modeling, a multifunctional land use network was constructed under the context of urban-rural integration. The evolution characteristics and driving mechanisms of this network were further explored. The findings indicated that: (1) with an increasing rural-urban integration, there existed an increase in node centrality, network density, and network reciprocity of both production function networks and living function networks in rural-urban areas. The spatial distribution followed a pattern of downstream > midstream > upstream. However, for ecological function networks, although node centrality decreased slightly with an increased integration level, there was little change in network density or reciprocity, showing a distribution patter of upstream > midstream > downstream. (2) Among the driving factors affecting production function networks, both rural-urban integration degree and its spatial lag term significantly inhibited node centrality, but positively promoted network density and reciprocity. （3）The analysis of living function network showed that the degree of urban-rural integration had a positive effect on the living function node centrality, network density and network reciprocity. （4）For ecological function networks, rural-urban integration did not have significant effects on node centrality, but had a significant positive impact on both network density and reciprocity. The results of this study are of great practical significance for realizing urban-rural integration and promoting regional sustainable development.