Abstract: Tourism integration is a trend of regional tourism economic development and cultural integration. The evolution of transportation network has an important impact on regional tourism integration. This influence is more obvious with the enhancement of accessibility. Taking the Poyang Lake area with the most concentrated distribution of tourism resources in Jiangxi Province as an example, this paper takes the evolution of the transportation network pattern in the region and its national tourism resources above Grade 3A as the research object, and carries out the evolution of the regional transportation network and its accessibility level. Based on the quantitative analysis, the grey relational coupling model is used to analyze the relationship between the communication network accessibility and the tourism economy. The study believes that: ①The degree of coupling between the accessibility of the transportation network in the Poyang Lake area and the tourism economic system is relatively high. The evolution and accessibility of the transportation network are crucial to the evolution of the tourism economy and the regional tourism integration pattern. There is a mutual feedback mechanism between the accessibility of the transportation network and the tourism economic system; ②The evolution of transportation network and the development stage of communication are different. The development and integration of regional tourism corresponds to different stage modes. It can be divided into point core mode, point axis corridor mode, multi-center ring axis mode and network integration mode. ③At present, tourism integration in the region has entered the primary stage of implementation. The focus of future development should focus on cooperation between tourism enterprises across administrative regions and the establishment of a unified tourism management coordination agency to provide reference for the development of regional tourism integration.