Abstract: Spatio-temporal heterogeneity and succession patterns of water quality were examined in Lake Changdang and Lake Gehu based on quarterly survey from February 2017 to November 2019 and historical data. The results showed that the main pollutants were total nitrogen (TN, inferior grade V), total phosphorus (TP, between grade Ⅲ and grade V) and permanganate index (CODMn, between grade Ⅱ and grade Ⅳ). In general，the trophic status of Lake Changdang and Lake Gehu were between light eutrophication and moderate eutrophication. The evolution trend analyzed of TN and TP and their relationship with social economic development factors were also analyzed based on literature research and remote sensing interpretation. The water quality of the two lakes continued to deteriorate, and the comprehensive water quality deteriorated from grade Ⅲ to grade V from 1990 to 2005. The water quality of the two lakes fluctuated greatly from 2006 to 2014. At this stage, it was mainly affected by a series of ecological restoration policies of Changzhou government (including the removal of the Seine net, the renovation of the catering industry in the lakes, the reduction of nitrogen and phosphorus). TN and TP concentrations was maintained at a relatively high level from 2017 to 2019. The species abundance and coverage of aquatic plants decreased sharply. After 2016, submerged plants in Lake Gehu almost disappeared, and the main dominant species changed from submerged plant Phragmites australis to emergent plant Phragmites australis. The significant positive relationships were calculated between TN or TP and social economic development factors through Spearman correlation analysis, while agricultural non-point source pollution, urbanization, industrialization and aquaculture were the main reasons for eutrophication. But enclosed aquaculture was not the decisive factor for eutrophication in Lake Changdang and Lake Gehu. So the eutrophication managements of Lake Changdang and Lake Gehu should follow the principles of “source controlling-reduction-restoration”. Furthermore, it is necessary to promote rural domestic sewage and livestock wastewater discharge standards, strengthen the protection of lakeshore zone and implement ecological restoration.